Patients at high risk of thromboembolic stroke who should be anticoagulated with warfarin unless contraindicated

Patients with no structural heart disease (INR 2-3)

Age 60 to 75 with diabetes mellitus or coronary heart disease
Age >75 with no risk factors

Patients with (INR 2-3):

Previous thromboembolic stroke
Heart failure
Left ventricular ejection fraction less than 35%
Thyrotoxicosis
Hypertension

Patients with (INR >2.5):

Rheumatic valve disease or prosthetic valves
Persistent atrial thrombus on echo